Shear Stress Induces Vasoprotective Gene Upregulation in Pericytes
نویسندگان
چکیده
منابع مشابه
Key transcriptional regulators of the vasoprotective effects of shear stress.
Atherosclerotic plaque rupture and subsequent thrombosis is the main cause of sudden coronary death. Remarkably, atherosclerosis only develops in certain predisposed areas of the vasculature. Endothelial cells in these predisposed areas experience low or oscillatory shear stress, which activates the proinflammatory and procoagulant transcription factors activator protein 1 (AP-1) and nuclear fa...
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ژورنال
عنوان ژورنال: European Journal of Vascular and Endovascular Surgery
سال: 2014
ISSN: 1078-5884
DOI: 10.1016/j.ejvs.2014.03.035